The Big Brain Podcast Ep. 2: DeFi Wizards

The BlockJune 13, 2025, 7:06AM EDT
UPDATED: June 16, 2025, 5:09AM EDT
The Big Brain Podcast Ep. 2: DeFi Wizards
Partner offers

Quick Take

  • Guy Young and Rune Christensen discuss the evolution of DeFi, noting how it has become more grounded in reality and sustainable business models, moving away from the early hype and ideological claims.
Advertisement

Episode 2 of The Big Brain Podcast, hosted by The Block's CEO Larry Cermak and MegaETH CSO Namik Muduroglu, was recorded with Ethena Founder Guy Young and Sky Protocol Co-Founder Rune Christensen.

Listen below, and subscribe to The Big Brain Podcast on YouTubeApple, Spotify or wherever you listen to podcasts. Please send feedback and revision requests to [email protected]


In this episode, Guy Young and Rune Christensen discuss the evolution of DeFi, noting how it has become more grounded in reality and sustainable business models, moving away from the early hype and ideological claims.

OUTLINE
00:00 Introduction
01:23
DeFi Ain't What it Used To Be
08:27 Ethena's Success
13:01 Get $HYPE(D)
15:08 HL L1
16:38 'Ecosystem Protocols'
19:32 DeFi User Capture
21:42 DeFi Endgame
22:05 Hyper-rational Users Onchain
24:53
Compressing DeFi Rates
27:16
Stealing  from the Rich
28:43 Onchain KYC
30:57 Forking DeFi
33:57 The Future of Finance
37:50 'MicroStrategy Playbook" for Alts
42:19 Bitcoin DeFi?
43:57 F.A.F.O. Onchain


The Block Newsletters
The Block's newsletters bring you the latest news and analysis of the fast-moving crypto and DeFi markets. To subscribe, visit theblock.co/newsletters

SHOW LINKS:
- Apple: https://apple.co/43F3vmq
- Spotify: https://spoti.fi/44NT1lZ
- Larry: https://x.com/lawmaster
- Namik: https://x.com/NamikMuduroglu
- The Block Podcasts: https://x.com/TheBlockPods

GUEST LINKS:
- Rune:@RuneKek
- Guy: @gdog97_
- Sky: https://sky.money/
- Ethena: https://ethena.fi/

Are you hiring in crypto?
Use Campus to quickly find your best candidates with our challenging Crypto Assessment Test.
Faster hiring, stronger teams.

Sign up for a trial today: theblock.co/campus


Disclaimer: The Block is an independent media outlet that delivers news, research, and data. As of November 2023, Foresight Ventures is a majority investor of The Block. Foresight Ventures invests in other companies in the crypto space. Crypto exchange Bitget is an anchor LP for Foresight Ventures. The Block continues to operate independently to deliver objective, impactful, and timely information about the crypto industry. Here are our current financial disclosures.

© 2025 The Block. All Rights Reserved. This article is provided for informational purposes only. It is not offered or intended to be used as legal, tax, investment, financial, or other advice.